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p53 Requires the Stress Sensor USF1 to Direct Appropriate Cell Fate Decision

Genomic instability is a major hallmark of cancer. To maintain genomic integrity, cells are equipped with dedicated sensors to monitor DNA repair or to force damaged cells into death programs. The tumor suppressor p53 is central in this process. Here, we report that the ubiquitous transcription fact...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bouafia, Amine, Corre, Sébastien, Gilot, David, Mouchet, Nicolas, Prince, Sharon, Galibert, Marie-Dominique
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022457/
https://ncbi.nlm.nih.gov/pubmed/24831529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004309
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