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Characterization of a new mouse p53 variant: loss-of-function and gain-of-function
BACKGROUND: p53 is a major tumor suppressor that is inactivated in over 50% of human cancer types through either mutation or inactivating interactions with viral or cellular proteins. The uncertainties around the link between p53 status, therapeutic response, and outcome in cancer suggest that addit...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4022406/ https://ncbi.nlm.nih.gov/pubmed/24884657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-21-40 |
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