The Structural Modeling of the Interaction between Levofloxacin and the Mycobacterium tuberculosis Gyrase Catalytic Site Sheds Light on the Mechanisms of Fluoroquinolones Resistant Tuberculosis in Colombian Clinical Isolates

We compared the prevalence of levofloxacin (LVX) resistance with that of ofloxacin (OFX) and moxifloxacin (MFX) among multidrug resistant (MDR) MTB clinical isolates collected in Medellin, Colombia, between 2004 and 2009 and aimed at unraveling the underlying molecular mechanisms that explain the co...

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Detalhes bibliográficos
Main Authors: Alvarez, N., Zapata, E., Mejía, G. I., Realpe, T., Araque, P., Peláez, C., Rouzaud, F., Robledo, J.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022255/
https://ncbi.nlm.nih.gov/pubmed/24877086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/367268
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