Non-stationary (13)C metabolic flux analysis of Chinese hamster ovary cells in batch culture using extracellular labeling highlights metabolic reversibility and compartmentation

BACKGROUND: Mapping the intracellular fluxes for established mammalian cell lines becomes increasingly important for scientific and economic reasons. However, this is being hampered by the high complexity of metabolic networks, particularly concerning compartmentation. RESULTS: Intracellular fluxes...

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Main Authors: Nicolae, Averina, Wahrheit, Judith, Bahnemann, Janina, Zeng, An-Ping, Heinzle, Elmar
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022241/
https://ncbi.nlm.nih.gov/pubmed/24773761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-8-50
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