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Genealogy Profiling through Strain Improvement by Using Metabolic Network Analysis: Metabolic Flux Genealogy of Several Generations of Lysine-Producing Corynebacteria

A comprehensive approach of metabolite balancing, (13)C tracer studies, gas chromatography-mass spectrometry, matrix-assisted laser desorption ionization-time of flight mass spectrometry, and isotopomer modeling was applied for comparative metabolic network analysis of a genealogy of five successive...

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Detalhes bibliográficos
Main Authors: Wittmann, Christoph, Heinzle, Elmar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134428/
https://ncbi.nlm.nih.gov/pubmed/12450803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.68.12.5843-5859.2002
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