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Dom34 Rescues Ribosomes in 3´ Untranslated Regions

Ribosomes that stall before completing peptide synthesis must be recycled and returned to the cytoplasmic pool. The protein Dom34 and cofactors Hbs1 and Rli1 can dissociate stalled ribosomes in vitro, but the identity of targets in the cell is unknown. Here we extend ribosome profiling methodology t...

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Bibliographic Details
Main Authors: Guydosh, Nicholas R., Green, Rachel
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022138/
https://ncbi.nlm.nih.gov/pubmed/24581494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.02.006
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