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Hedgehog Signaling Controls T Cell Killing at the Immunological Synapse
The centrosome is essential for cytotoxic T lymphocyte (CTL) function, contacting the plasma membrane and directing cytotoxic granules for secretion at the immunological synapse. Centrosome docking at the plasma membrane also occurs during cilia formation. The primary cilium, formed in nonhematopoie...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4022134/ https://ncbi.nlm.nih.gov/pubmed/24311692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1244689 |
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