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Hedgehog Signaling Controls T Cell Killing at the Immunological Synapse

The centrosome is essential for cytotoxic T lymphocyte (CTL) function, contacting the plasma membrane and directing cytotoxic granules for secretion at the immunological synapse. Centrosome docking at the plasma membrane also occurs during cilia formation. The primary cilium, formed in nonhematopoie...

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Podrobná bibliografie
Hlavní autoři: de la Roche, Maike, Ritter, Alex T., Angus, Karen L., Dinsmore, Colin, Earnshaw, Charles H., Reiter, Jeremy F., Griffiths, Gillian M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022134/
https://ncbi.nlm.nih.gov/pubmed/24311692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1244689
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