Centrosome docking at the immunological synapse is controlled by Lck signaling

Docking of the centrosome at the plasma membrane directs lytic granules to the immunological synapse. To identify signals controlling centrosome docking at the synapse, we have studied cytotoxic T lymphocytes (CTLs) in which expression of the T cell receptor–activated tyrosine kinase Lck is ablated....

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Autors principals: Tsun, Andy, Qureshi, Ihjaaz, Stinchcombe, Jane C., Jenkins, Misty R., de la Roche, Maike, Kleczkowska, Joanna, Zamoyska, Rose, Griffiths, Gillian M.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2011
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044125/
https://ncbi.nlm.nih.gov/pubmed/21339332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201008140
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