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IDH Mutations: Genotype-Phenotype Correlation and Prognostic Impact
IDH1/2 mutation is the most frequent genomic alteration found in gliomas, affecting 40% of these tumors and is one of the earliest alterations occurring in gliomagenesis. We investigated a series of 1305 gliomas and showed that IDH mutation is almost constant in 1p19q codeleted tumors. We found that...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Hindawi Publishing Corporation
2014
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4022066/ https://ncbi.nlm.nih.gov/pubmed/24877111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/540236 |
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