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Dysregulated phosphorylation of Ca(2+)/calmodulin-dependent protein kinase II-α in the hippocampus of subjects with mild cognitive impairment and Alzheimer’s disease

Alzheimer’s Disease (AD) is a progressive, neurodegenerative disorder and the most prevalent senile dementia. The early symptom of memory dysfunction involves synaptic loss, thought to be mediated by soluble amyloid-beta (Aβ) oligomers. These aggregate species target excitatory synapses and their le...

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Autors principals: Reese, Lindsay C., Laezza, Fernanda, Woltjer, Randall, Taglialatela, Giulio
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021864/
https://ncbi.nlm.nih.gov/pubmed/21883216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2011.07447.x
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