BRAFV600E immunohistochemistry in conjunction with mismatch repair status predicts survival in patients with colorectal cancer

Immunohistochemistry has recently been validated for the detection of the BRAFV600E mutation across a range of tumor types. In colorectal carcinoma, the presence of the BRAFV600E mutation can be used to virtually exclude Lynch syndrome in mismatch repair-deficient tumors. In mismatch repair-proficie...

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Hlavní autoři: Toon, Christopher W, Chou, Angela, DeSilva, Keshani, Chan, Joseph, Patterson, Jillian, Clarkson, Adele, Sioson, Loretta, Jankova, Lucy, Gill, Anthony J
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021849/
https://ncbi.nlm.nih.gov/pubmed/24157612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2013.200
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