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Alpha fetoprotein DNA prime and adenovirus boost immunization of two hepatocellular cancer patients
BACKGROUND: Alpha fetoprotein (AFP) is an oncofetal antigen over-expressed by many hepatocellular cancers (HCC). We previously demonstrated that HLA-A2-restricted epitopes derived from AFP are immunogenic in vitro and in vivo despite high circulating levels of this oncofetal antigen. In order to tes...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4021640/ https://ncbi.nlm.nih.gov/pubmed/24708667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-86 |
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