Antibody therapy can enhance AngiotensinII-induced myocardial fibrosis

BACKGROUND: Myocardial fibrosis is a pathological process that is characterized by disrupted regulation of extracellular matrix proteins resulting in permanent scarring of the heart tissue and eventual diastolic heart failure. Pro-fibrotic molecules including transforming growth factor-β and connect...

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Autores principales: Rosin, Nicole L, Gareau, Alison J, Betsch, Devin, Falkenham, Alec, Sopel, Mryanda J, Lee, Timothy DG, Légaré, Jean-Francois
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021636/
https://ncbi.nlm.nih.gov/pubmed/24721281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-7-6
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