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Investigating the relationship between mitochondrial genetic variation and cardiovascular-related traits to develop a framework for mitochondrial phenome-wide association studies

BACKGROUND: Mitochondria play a critical role in the cell and have DNA independent of the nuclear genome. There is much evidence that mitochondrial DNA (mtDNA) variation plays a role in human health and disease, however, this area of investigation has lagged behind research into the role of nuclear...

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Bibliographische Detailangaben
Hauptverfasser:	Mitchell, Sabrina L, Hall, Jacob B, Goodloe, Robert J, Boston, Jonathan, Farber-Eger, Eric, Pendergrass, Sarah A, Bush, William S, Crawford, Dana C
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BioMed Central 2014
Schlagworte:	Research
Online Zugang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4021623/ https://ncbi.nlm.nih.gov/pubmed/24731735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0381-7-6
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Investigating the relationship between mitochondrial genetic variation and cardiovascular-related traits to develop a framework for mitochondrial phenome-wide association studies

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