Investigating the relationship between mitochondrial genetic variation and cardiovascular-related traits to develop a framework for mitochondrial phenome-wide association studies

BACKGROUND: Mitochondria play a critical role in the cell and have DNA independent of the nuclear genome. There is much evidence that mitochondrial DNA (mtDNA) variation plays a role in human health and disease, however, this area of investigation has lagged behind research into the role of nuclear...

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Detalhes bibliográficos
Main Authors: Mitchell, Sabrina L, Hall, Jacob B, Goodloe, Robert J, Boston, Jonathan, Farber-Eger, Eric, Pendergrass, Sarah A, Bush, William S, Crawford, Dana C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021623/
https://ncbi.nlm.nih.gov/pubmed/24731735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0381-7-6
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