Hanging drop cultures of human testis and testis cancer samples: a model used to investigate activin treatment effects in a preserved niche

BACKGROUND: Testicular germ cell tumours of young adults, seminoma or non-seminomas, are preceded by a pre-invasive precursor, carcinoma in situ (CIS), understood to arise through differentiation arrest of embryonic germ cells. Knowledge about the malignant transformation of germ cells is currently...

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Detalhes bibliográficos
Main Authors: Jørgensen, A, Young, J, Nielsen, J E, Joensen, U N, Toft, B G, Rajpert-De Meyts, E, Loveland, K L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021512/
https://ncbi.nlm.nih.gov/pubmed/24781282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.160
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