Kinetics of mycolactone in human subcutaneous tissue during antibiotic therapy for Mycobacterium ulcerans disease

BACKGROUND: Mycobacterium ulcerans (M. ulcerans) causes a devastating necrotising infection of skin tissue leading to progressive ulceration. M. ulcerans is the only human pathogen that secretes mycolactone, a polyketide molecule with potent cytotoxic and immunomodulatory properties. These unique fe...

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Bibliographic Details
Main Authors: Sarfo, Fred S, Phillips, Richard O, Zhang, Jihui, Abass, Mohammed K, Abotsi, Justice, Amoako, Yaw A, Adu-Sarkodie, Yaw, Robinson, Clive, Wansbrough-Jones, Mark H
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021496/
https://ncbi.nlm.nih.gov/pubmed/24731247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-14-202
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