Kinetics of mycolactone in human subcutaneous tissue during antibiotic therapy for Mycobacterium ulcerans disease

BACKGROUND: Mycobacterium ulcerans (M. ulcerans) causes a devastating necrotising infection of skin tissue leading to progressive ulceration. M. ulcerans is the only human pathogen that secretes mycolactone, a polyketide molecule with potent cytotoxic and immunomodulatory properties. These unique fe...

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Detalhes bibliográficos
Main Authors: Sarfo, Fred S, Phillips, Richard O, Zhang, Jihui, Abass, Mohammed K, Abotsi, Justice, Amoako, Yaw A, Adu-Sarkodie, Yaw, Robinson, Clive, Wansbrough-Jones, Mark H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021496/
https://ncbi.nlm.nih.gov/pubmed/24731247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-14-202
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