Frataxin-bypassing Isu1: characterization of the bypass activity in cells and mitochondria

Frataxin is a conserved mitochondrial protein, and deficiency underlies the neurodegenerative disease Friedreich’s ataxia. Frataxin interacts with the core machinery for Fe–S cluster assembly in mitochondria. Recently we reported that in frataxin-deleted yeast strains, a spontaneously occurring muta...

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Bibliografiske detaljer
Main Authors: Yoon, Heeyong, Knight, Simon A. B., Pandey, Alok, Pain, Jayashree, Zhang, Yan, Pain, Debkumar, Dancis, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021491/
https://ncbi.nlm.nih.gov/pubmed/24433162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20131273
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