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Simvastatin attenuates rhinovirus-induced interferon and CXCL10 secretion from monocytic cells in vitro

RV infections frequently trigger exacerbations of respiratory diseases, such as asthma, yet treatment and intervention options remain limited. Statin drugs are the treatment of choice for dyslipidemia and can also modulate immune cell function. To determine whether statin drugs modify antiviral resp...

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Detalhes bibliográficos
Main Authors: Wickert, Lisa E., Karta, Maya R., Audhya, Anjon, Gern, James E., Bertics, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021432/
https://ncbi.nlm.nih.gov/pubmed/24532643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0713413
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