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Non-specificity of Pitstop 2 in clathrin-mediated endocytosis

Small molecule inhibitors of clathrin-mediated endocytosis are highly desired for the dissection of membrane trafficking pathways in the lab and for potential use as anti-infectives in the clinic. One inhibition strategy is to prevent clathrin from contacting adaptor proteins so that clathrin-mediat...

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Detalhes bibliográficos
Main Authors: Willox, Anna K., Sahraoui, Yasmina M. E., Royle, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021354/
https://ncbi.nlm.nih.gov/pubmed/24705016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20147955
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