Rapid fitness losses in mammalian RNA virus clones due to Muller's ratchet.
Muller's ratchet is an important concept in population genetics. It predicts that when mutation rates are high and a significant proportion of mutations are deleterious, a kind of irreversible ratchet mechanism will gradually decrease the mean fitness of small populations of asexual organisms. In co...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1992
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC402129/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1321432/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.13.6015 |
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