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Rapid fitness losses in mammalian RNA virus clones due to Muller's ratchet.

Muller's ratchet is an important concept in population genetics. It predicts that when mutation rates are high and a significant proportion of mutations are deleterious, a kind of irreversible ratchet mechanism will gradually decrease the mean fitness of small populations of asexual organisms....

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Bibliografiska uppgifter
Huvudupphovsmän: Duarte, E, Clarke, D, Moya, A, Domingo, E, Holland, J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1992
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC402129/
https://ncbi.nlm.nih.gov/pubmed/1321432
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