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Allosteric and Biased G Protein-Coupled Receptor Signaling Regulation: Potentials for New Therapeutics
G protein-coupled receptors (GPCRs) are seven-transmembrane proteins that participate in many aspects of the endocrine function and are important targets for drug development. They transduce signals mainly, but not exclusively, via hetero-trimeric G proteins, leading to a diversity of intracellular...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4021147/ https://ncbi.nlm.nih.gov/pubmed/24847311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2014.00068 |
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