Cellular Uptake and Antitumor Activity of DOX-hyd-PEG-FA Nanoparticles

A PEG-based, folate mediated, active tumor targeting drug delivery system using DOX-hyd-PEG-FA nanoparticles (NPs) were prepared. DOX-hyd-PEG-FA NPs showed a significantly faster DOX release in pH 5.0 medium than in pH 7.4 medium. Compared with DOX-hyd-PEG NPs, DOX-hyd-PEG-FA NPs increased the intra...

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Detalhes bibliográficos
Main Authors: Ye, Wei-liang, Du, Jiang-bo, Zhang, Bang-le, Na, Ren, Song, Yan-feng, Mei, Qi-bing, Zhao, Ming-gao, Zhou, Si-yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020841/
https://ncbi.nlm.nih.gov/pubmed/24828815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097358
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