Mononuclear Phagocytes and Airway Epithelial Cells: Novel Sources of Matrix Metalloproteinase-8 (MMP-8) in Patients with Idiopathic Pulmonary Fibrosis

OBJECTIVES: Matrix metalloproteinase-8 (MMP-8) promotes lung fibrotic responses to bleomycin in mice. Although prior studies reported that MMP-8 levels are increased in plasma and bronchoalveolar lavage fluid (BALF) samples from IPF patients, neither the bioactive forms nor the cellular sources of M...

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Autori principali: Craig, Vanessa J., Polverino, Francesca, Laucho-Contreras, Maria E., Shi, Yuanyuan, Liu, Yushi, Osorio, Juan C., Tesfaigzi, Yohannes, Pinto-Plata, Victor, Gochuico, Bernadette R., Rosas, Ivan O., Owen, Caroline A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020836/
https://ncbi.nlm.nih.gov/pubmed/24828408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097485
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