The Ganglioside GM3 Is Associated with Cisplatin-Induced Apoptosis in Human Colon Cancer Cells

Cisplatin (cis-diamminedichloroplatinum, CDDP) is a well-known chemotherapeutic agent for the treatment of several cancers. However, the precise mechanism underlying apoptosis of cancer cells induced by CDDP remains unclear. In this study, we show mechanistically that CDDP induces GM3-mediated apopt...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Chung, Tae-Wook, Choi, Hee-Jung, Kim, Seok-Jo, Kwak, Choong-Hwan, Song, Kwon-Ho, Jin, Un-Ho, Chang, Young-Chae, Chang, Hyeun Wook, Lee, Young-Choon, Ha, Ki-Tae, Kim, Cheorl-Ho
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2014
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020741/
https://ncbi.nlm.nih.gov/pubmed/24829158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092786
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