The Ganglioside GM3 Is Associated with Cisplatin-Induced Apoptosis in Human Colon Cancer Cells

Cisplatin (cis-diamminedichloroplatinum, CDDP) is a well-known chemotherapeutic agent for the treatment of several cancers. However, the precise mechanism underlying apoptosis of cancer cells induced by CDDP remains unclear. In this study, we show mechanistically that CDDP induces GM3-mediated apopt...

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Opis bibliograficzny
Główni autorzy: Chung, Tae-Wook, Choi, Hee-Jung, Kim, Seok-Jo, Kwak, Choong-Hwan, Song, Kwon-Ho, Jin, Un-Ho, Chang, Young-Chae, Chang, Hyeun Wook, Lee, Young-Choon, Ha, Ki-Tae, Kim, Cheorl-Ho
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2014
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020741/
https://ncbi.nlm.nih.gov/pubmed/24829158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092786
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