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The Ganglioside GM3 Is Associated with Cisplatin-Induced Apoptosis in Human Colon Cancer Cells

Cisplatin (cis-diamminedichloroplatinum, CDDP) is a well-known chemotherapeutic agent for the treatment of several cancers. However, the precise mechanism underlying apoptosis of cancer cells induced by CDDP remains unclear. In this study, we show mechanistically that CDDP induces GM3-mediated apopt...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chung, Tae-Wook, Choi, Hee-Jung, Kim, Seok-Jo, Kwak, Choong-Hwan, Song, Kwon-Ho, Jin, Un-Ho, Chang, Young-Chae, Chang, Hyeun Wook, Lee, Young-Choon, Ha, Ki-Tae, Kim, Cheorl-Ho
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020741/
https://ncbi.nlm.nih.gov/pubmed/24829158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092786
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