The Ganglioside GM3 Is Associated with Cisplatin-Induced Apoptosis in Human Colon Cancer Cells

Cisplatin (cis-diamminedichloroplatinum, CDDP) is a well-known chemotherapeutic agent for the treatment of several cancers. However, the precise mechanism underlying apoptosis of cancer cells induced by CDDP remains unclear. In this study, we show mechanistically that CDDP induces GM3-mediated apopt...

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Detalhes bibliográficos
Main Authors: Chung, Tae-Wook, Choi, Hee-Jung, Kim, Seok-Jo, Kwak, Choong-Hwan, Song, Kwon-Ho, Jin, Un-Ho, Chang, Young-Chae, Chang, Hyeun Wook, Lee, Young-Choon, Ha, Ki-Tae, Kim, Cheorl-Ho
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020741/
https://ncbi.nlm.nih.gov/pubmed/24829158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092786
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