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Tissue concentration of systemically administered antineoplastic agents in human brain tumors
The blood–brain-barrier (BBB) limits the penetration of many systemic antineoplastic therapies. Consequently, many agents may be used in clinical studies and clinical practice though they may not achieve therapeutic levels within the tumor. We sought to compile the currently available human data on...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4020433/ https://ncbi.nlm.nih.gov/pubmed/21400119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-011-0564-y |
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