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Orally Administered Bifidobacteria as Vehicles for Delivery of Agents to Systemic Tumors

Certain bacteria have emerged as biological gene vectors with natural tumor specificity, capable of specifically delivering genes or gene products to the tumor environment when intravenously (i.v.) administered to rodent models. We show for the first time that oral administration of bacteria to mice...

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Detalhes bibliográficos
Main Authors: Cronin, Michelle, Morrissey, David, Rajendran, Simon, El Mashad, Shereen M, van Sinderen, Douwe, O'Sullivan, Gerald C, Tangney, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911250/
https://ncbi.nlm.nih.gov/pubmed/20389288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.59
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