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Orally Administered Bifidobacteria as Vehicles for Delivery of Agents to Systemic Tumors

Certain bacteria have emerged as biological gene vectors with natural tumor specificity, capable of specifically delivering genes or gene products to the tumor environment when intravenously (i.v.) administered to rodent models. We show for the first time that oral administration of bacteria to mice...

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Autors principals: Cronin, Michelle, Morrissey, David, Rajendran, Simon, El Mashad, Shereen M, van Sinderen, Douwe, O'Sullivan, Gerald C, Tangney, Mark
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911250/
https://ncbi.nlm.nih.gov/pubmed/20389288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.59
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