Chrysophanol Inhibits NALP3 Inflammasome Activation and Ameliorates Cerebral Ischemia/Reperfusion in Mice

The most effective way to contain cerebral ischemic injury is reperfusion; however, reperfusion itself may result in tissue injury, for which inflammatory damage is one of the main causative factors. NALP3 inflammasome is a multiprotein complex. It consists of NALP3, ASC, and caspase-1, whose functi...

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Hlavní autoři: Zhang, Nan, Zhang, Xiangjian, Liu, Xiaoxia, Wang, Hong, Xue, Jing, Yu, Jingying, Kang, Ning, Wang, Xiaolu
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020303/
https://ncbi.nlm.nih.gov/pubmed/24876671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/370530
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