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Effects of side chains in helix nucleation differ from helix propagation

Helix–coil transition theory connects observable properties of the α-helix to an ensemble of microstates and provides a foundation for analyzing secondary structure formation in proteins. Classical models account for cooperative helix formation in terms of an energetically demanding nucleation event...

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Autori principali: Miller, Stephen E., Watkins, Andrew M., Kallenbach, Neville R., Arora, Paramjit S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020114/
https://ncbi.nlm.nih.gov/pubmed/24753597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322833111
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