The Role of HGF/c-Met Signaling in Prostate Cancer Progression and c-Met Inhibitors in Clinical Trials

INTRODUCTION: An increasing number of basic, translational and clinical studies demonstrate the importance of the protein tyrosine kinase receptor, c-Met, in the progression of prostate cancer. c-Met is overexpressed in primary prostate cancers, further increased in expression in bone metastases and...

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Main Authors: Varkaris, Andreas, Corn, Paul G., Gaur, Sanchaika, Dayyani, Farshid, Logothetis, Christopher J., Gallick, Gary E.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020016/
https://ncbi.nlm.nih.gov/pubmed/22035268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543784.2011.631523
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