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Immunoglobulin-like transcript 2 (ILT2) is a biomarker of therapeutic response to oncolytic immunotherapy with vaccinia viruses

BACKGROUND: Oncolytic viruses represent a novel form of cancer immunotherapy. Vaccinia viruses encoding human T cell co-stimulatory molecules have demonstrated clinical activity in phase I clinical trials in patients with advanced melanoma. However, predictive biomarkers of therapeutic response have...

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Detalhes bibliográficos
Main Authors: Zloza, Andrew, Kim, Dae Won, Kim-Schulze, Seunghee, Jagoda, Michael C, Monsurro, Vladia, Marincola, Francesco M, Kaufman, Howard L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019911/
https://ncbi.nlm.nih.gov/pubmed/24829758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-1426-2-1
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