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A Chromosome 21 Critical Region Does Not Cause Specific Down Syndrome Phenotypes
The “Down syndrome critical region” (DSCR) is a chromosome 21 segment purported to contain genes responsible for many features of Down syndrome (DS), including craniofacial dysmorphology. We used chromosome engineering to create mice that were trisomic or monosomic for only the mouse chromosome segm...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4019810/ https://ncbi.nlm.nih.gov/pubmed/15499018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1098992 |
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