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Molecular definition of a region of chromosome 21 that causes features of the Down syndrome phenotype

Down syndrome (DS) is a major cause of mental retardation and heart disease. Although it is usually caused by the presence of an extra chromosome 21, a subset of the diagnostic features may be caused by the presence of only band 21q22. We now present evidence that significantly narrows the chromosom...

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Main Authors: Korenberg, Julie R., Kawashima, Hiroko, Pulst, Stefan-M., Ikeuchi, T., Ogasawara, N., Yamamoto, K., Schonberg, Steven A., West, Ruth, Allen, Leland, Magenis, Ellen, Ikawa, K., Taniguchi, N., Epstein, Charles J.
格式: Artigo
語言:Inglês
出版: 1990
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1683719/
https://ncbi.nlm.nih.gov/pubmed/2143053
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