Activation of Neurotensin Receptor 1 Facilitates Neuronal Excitability and Spatial Learning and Memory in the Entorhinal Cortex: Beneficial Actions in an Alzheimer's Disease Model

Neurotensin (NT) is a tridecapeptide distributed in the CNS, including the entorhinal cortex (EC), a structure that is crucial for learning and memory and undergoes the earliest pathological alterations in Alzheimer's disease (AD). Whereas NT has been implicated in modulating cognition, the cel...

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Détails bibliographiques
Auteurs principaux: Xiao, Zhaoyang, Cilz, Nicholas I., Kurada, Lalitha, Hu, Binqi, Yang, Chuanxiu, Wada, Etsuko, Combs, Colin K., Porter, James E., Lesage, Florian, Lei, Saobo
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2014
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019809/
https://ncbi.nlm.nih.gov/pubmed/24828655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0408-14.2014
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