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Corticotropin-Releasing Factor Facilitates Epileptiform Activity in the Entorhinal Cortex: Roles of CRF(2) Receptors and PKA Pathway

Whereas corticotropin-releasing factor (CRF) has been considered as the most potent epileptogenic neuropeptide in the brain, its action site and underlying mechanisms in epilepsy have not been determined. Here, we found that the entorhinal cortex (EC) expresses high level of CRF and CRF(2) receptors...

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Autores principales: Kurada, Lalitha, Yang, Chuanxiu, Lei, Saobo
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913751/
https://ncbi.nlm.nih.gov/pubmed/24505399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088109
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