Caveolin-1 is critical for abdominal aortic aneurysm formation induced by angiotensin II and inhibition of lysyl oxidase

Although angiotensin II (Ang II) and its receptor AT(1) have been implicated in abdominal aortic aneurysm (AAA) formation, the proximal signaling events primarily responsible for AAA formation remain uncertain. Caveolae are cholesterol-rich membrane microdomains that serve as a signaling platform to...

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Autores principales: Takayanagi, Takehiko, Crawford, Kevin J., Kobayashi, Tomonori, Obama, Takashi, Tsuji, Toshiyuki, Elliott, Katherine J., Hashimoto, Tomoki, Rizzo, Victor, Eguchi, Satoru
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019733/
https://ncbi.nlm.nih.gov/pubmed/24329494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20130660
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