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Aprotinin, but not epsilon aminocaproic acid and tranexamic acid, exerts neuroprotection against excitotoxic injury in an in vitro neuronal cell culture model

OBJECTIVE: Lack of availability of aprotinin has resulted in increased clinical use of the alternative antifibrinolytic agents epsilon aminocaproic acid (EACA) and tranexamic acid (TXA) which are known to be associated with an increased risk of seizures. In contrast aprotinin has previously been dem...

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Détails bibliographiques
Auteurs principaux: Lu, Zhaohui, Korotcova, Ludmila, Murata, Akira, Ishibashi, Nobuyuki, Jonas, Richard A.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019727/
https://ncbi.nlm.nih.gov/pubmed/24237885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2013.09.054
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