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Sorting Through the Roles of Beclin 1 in Microglia and Neurodegeneration

Beclin 1 has a well-established role in regulating autophagy, a cellular degradation pathway. Although the yeast ortholog of beclin 1 (Atg6/Vps30) was discovered to also regulate vacuolar protein sorting nearly 30 years ago, the varied functions of beclin 1 in mammalian cells are only beginning to b...

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Détails bibliographiques
Auteurs principaux: O’Brien, Caitlin E., Wyss-Coray, Tony
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019692/
https://ncbi.nlm.nih.gov/pubmed/24385262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-013-9519-8
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