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Nucleophosmin modulates stability, activity, and nucleolar accumulation of base excision repair proteins

Nucleophosmin (NPM1) is a multifunctional protein that controls cell growth and genome stability via a mechanism that involves nucleolar–cytoplasmic shuttling. It is clear that NPM1 also contributes to the DNA damage response, yet its exact function is poorly understood. We recently linked NPM1 expr...

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Detalhes bibliográficos
Main Authors: Poletto, Mattia, Lirussi, Lisa, Wilson, David M., Tell, Gianluca
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019495/
https://ncbi.nlm.nih.gov/pubmed/24648491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-12-0717
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