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Methods for Specifying the Target Difference in a Randomised Controlled Trial: The Difference ELicitation in TriAls (DELTA) Systematic Review

BACKGROUND: Randomised controlled trials (RCTs) are widely accepted as the preferred study design for evaluating healthcare interventions. When the sample size is determined, a (target) difference is typically specified that the RCT is designed to detect. This provides reassurance that the study wil...

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Autors principals: Hislop, Jenni, Adewuyi, Temitope E., Vale, Luke D., Harrild, Kirsten, Fraser, Cynthia, Gurung, Tara, Altman, Douglas G., Briggs, Andrew H., Fayers, Peter, Ramsay, Craig R., Norrie, John D., Harvey, Ian M., Buckley, Brian, Cook, Jonathan A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019477/
https://ncbi.nlm.nih.gov/pubmed/24824338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1001645
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