Rapid Transport of CCL11 across the Blood-Brain Barrier: Regional Variation and Importance of Blood Cells

Increased blood levels of the eotaxin chemokine C-C motif ligand 11 (CCL11) in aging were recently shown to negatively regulate adult hippocampal neurogenesis. How circulating CCL11 could affect the central nervous system (CNS) is not clear, but one possibility is that it can cross the blood-brain b...

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Bibliographic Details
Main Authors: Erickson, Michelle A., Morofuji, Yoichi, Owen, Joshua B., Banks, William A.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2014
Subjects:
Neuropharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019322/
https://ncbi.nlm.nih.gov/pubmed/24706984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.213074
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