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Vaccination with a Single CD4 T Cell Peptide Epitope from a Salmonella Type III-Secreted Effector Protein Provides Protection against Lethal Infection

Salmonella infections affect millions worldwide and remain a significant cause of morbidity and mortality. It is known from mouse studies that CD4 T cells are essential mediators of immunity against Salmonella infection, yet it is not clear whether targeting CD4 T cell responses directly with peptid...

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Bibliografiske detaljer
Main Authors: Kurtz, Jonathan R, Petersen, Hailey E., Frederick, Daniel R., Morici, Lisa A., McLachlan, James B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019158/
https://ncbi.nlm.nih.gov/pubmed/24686055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00052-14
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