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Type I Interferon Signaling Regulates Activation of the Absent in Melanoma 2 Inflammasome during Streptococcus pneumoniae Infection

Streptococcus pneumoniae, a Gram-positive bacterial pathogen, causes pneumonia, meningitis, and septicemia. Innate immune responses are critical for the control and pathology of pneumococcal infections. It has been demonstrated that S. pneumoniae induces the production of type I interferons (IFNs) b...

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Detalhes bibliográficos
Main Authors: Fang, Rendong, Hara, Hideki, Sakai, Shunsuke, Hernandez-Cuellar, Eduardo, Mitsuyama, Masao, Kawamura, Ikuo, Tsuchiya, Kohsuke
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019145/
https://ncbi.nlm.nih.gov/pubmed/24643540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01572-14
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