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Cytosolic-DNA-Mediated, STING-Dependent Proinflammatory Gene Induction Necessitates Canonical NF-κB Activation through TBK1

STING (stimulator of interferon genes) is known to control the induction of innate immune genes in response to the recognition of cytosolic DNA species, including the genomes of viruses such as herpes simplex virus 1 (HSV-1). However, while STING is essential for protection of the host against numer...

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Bibliografiska uppgifter
Huvudupphovsmän: Abe, Takayuki, Barber, Glen N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019140/
https://ncbi.nlm.nih.gov/pubmed/24600004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00037-14
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