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Nelfinavir Inhibits Maturation and Export of Herpes Simplex Virus 1

Nelfinavir (NFV) is an HIV-1 protease inhibitor with demonstrated antiviral activity against herpes simplex virus 1 (HSV-1) and several other herpesviruses. However, the stages of HSV-1 replication inhibited by NFV have not been explored. In this study, we investigated the effects of NFV on capsid a...

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Bibliographic Details
Main Authors: Kalu, Nene N., Desai, Prashant J., Shirley, Courtney M., Gibson, Wade, Dennis, Phillip A., Ambinder, Richard F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019105/
https://ncbi.nlm.nih.gov/pubmed/24574416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03790-13
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