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Identification of Alternative Transcripts Encoding the Essential Murine Gammaherpesvirus Lytic Transactivator RTA

The essential immediate early transcriptional activator RTA, encoded by gene 50, is conserved among all characterized gammaherpesviruses. Analyses of a recombinant murine gammaherpesvirus 68 (MHV68) lacking both of the known gene 50 promoters (G50DblKo) revealed that this mutant retained the ability...

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Autori principali: Wakeman, Brian S., Johnson, L. Steven, Paden, Clinton R., Gray, Kathleen S., Virgin, Herbert W., Speck, Samuel H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019092/
https://ncbi.nlm.nih.gov/pubmed/24574412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03110-13
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